Effects of primaquine and chloroquine on oxidative stress parameters in rats

Effects of primaquine and chloroquine on oxidative stress parameters in rats

Primaquine and chloroquine are used for the treatment of malaria; evidence from the literature suggests that these drugs may induce oxidative stress. In this study we investigated the effects of primaquine and chloroquine on oxidative damage and DNA damage in brain, liver and kidney of rats after 7,...

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Main Authors: FRANCIANNE GIOVANELLA, GABRIELA K. FERREIRA, SAMIRA D.T. DE PRÁ, MILENA CARVALHO-SILVA, LARA M. GOMES, GISELLI SCAINI, RENATA C. GONÇALVES, MONIQUE MICHELS, LETÍCIA S. GALANT, LUIZA M. LONGARETTI, ANA LUIZA DAJORI, VANESSA M. ANDRADE, FELIPE DAL-PIZZOL, EMILIO L. STRECK, RENAN P. DE SOUZA
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2015-08-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
primaquina
cloroquina
dano oxidativo
dano ao DNA
antimaláricos
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301487&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301487&lng=en&tlng=en

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