Dupuytren’s and Ledderhose Diseases in a Family with LMNA-Related Cardiomyopathy and a Novel Variant in the ASTE1 Gene

Dupuytren’s and Ledderhose Diseases in a Family with LMNA-Related Cardiomyopathy and a Novel Variant in the ASTE1 Gene

Dupuytren’s disease (palmar fibromatosis) involves nodules in fascia of the hand that leads to flexion contractures. Ledderhose disease (plantar fibromatosis) is similar with nodules of the foot. While clinical aspects are well-described, genetic mechanisms are unknown. We report a family with cardi...

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Bibliographic Details
Main Authors: Michael V. Zaragoza, Cecilia H. H. Nguyen, Halida P. Widyastuti, Linda A. McCarthy, Anna Grosberg
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Cells
Subjects:
LMNA gene
lamin
cardiomyopathy
arrhythmias
Dupuytren’s disease
Ledderhose disease
fibromatosis
genetic susceptibility
ASTE1 gene
Online Access:https://www.mdpi.com/2073-4409/6/4/40

Internet

https://www.mdpi.com/2073-4409/6/4/40

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