A Mouse Ependymoma Model Provides Molecular Insights into Tumor Formation

Ozawa et al. present a murine tumor model resembling the most frequent molecular group of human supratentorial ependymoma, ST-EPN-RELA. Their model shows RELA-fusion-based de novo ependymoma tumorigenesis in the forebrain derived from neural stem cells. : Ozawa et al. present a murine tumor model re...

Full description

Bibliographic Details
Main Authors: Kristian W. Pajtler, Stefan M. Pfister
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718309896