The origin recognition complex in human diseases

ORC (origin recognition complex) serves as the initiator for the assembly of the pre-RC (pre-replication complex) and the subsequent DNA replication. Together with many of its non-replication functions, ORC is a pivotal regulator of various cellular processes. Notably, a number of reports connect OR...

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Bibliographic Details
Main Author: Zhen Shen
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2013-06-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/033/e044/bsr033e044.htm