Multiplex Genome Editing in Chinese Hamster Ovary Cell Line Using All-in-One and HITI CRISPR Technology

Purpose: CRISPR/Cas9 gene editing technology has revolutionized gene manipulation by providing the opportunity of gene knock out/in, transcriptional modification and base editing. The application of this system extended into different eras of biology, from cell development to animal modeling. Variou...

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Bibliographic Details
Main Authors: Fatemeh Safari, Safar Farajnia, Younes Ghasemi, Nosratollah Zarghami, Mazyar Barekati Mowahed
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2021-02-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-11-343.pdf