Memory CD8+ T cell compartment associated with delayed onset of Plasmodium falciparum infection and better parasite control in sickle‐cell trait children

Memory CD8+ T cell compartment associated with delayed onset of Plasmodium falciparum infection and better parasite control in sickle‐cell trait children

Abstract Objectives Study of individuals with protection from Plasmodium falciparum (Pf) infection and clinical malaria, including individuals affected by the sickle‐cell trait (HbAS), offers the potential to identify cellular targets that could be translated for therapeutic development. We previous...

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Bibliographic Details
Main Authors: Claire Loiseau, Boubacar Traore, Aissata Ongoiba, Kassoum Kayentao, Safiatou Doumbo, Didier Doumtabe, Karina P deSousa, Jamie L Brady, Carla Proietti, Peter D Crompton, Denise L Doolan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
haemoglobin AS
memory CD8+ T cells
Plasmodium falciparum
protective immunity
sickle‐cell trait phenotype
Online Access:https://doi.org/10.1002/cti2.1265

Internet

https://doi.org/10.1002/cti2.1265

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