Tcf7L2 is essential for neurogenesis in the developing mouse neocortex

Abstract Generation of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells in the ventricular zone and for differentiation of intermediate progenitors in th...

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Bibliographic Details
Main Authors: Olga Chodelkova, Jan Masek, Vladimir Korinek, Zbynek Kozmik, Ondrej Machon
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Neural Development
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13064-018-0107-8