Nod-like receptors: cytosolic watchdogs for immunity against pathogens.

In mammals, tissue-specific sets of pattern-recognition molecules, including Nod-like receptors (NLR), enable concomitant and sequential detection of microbial-associated molecular patterns from both the extracellular and intracellular microenvironment. Repressing and de-repressing the cytosolic sur...

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Bibliographic Details
Main Authors: Jean-Claude Sirard, Cécile Vignal, Rodrigue Dessein, Mathias Chamaillard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18166077/?tool=EBI