Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer’s disease

Brain metabolic dysfunction is known to influence brain activity in several neurological disorders, including Alzheimer’s disease (AD). In fact, deregulation of neuronal metabolism has been postulated to play a key role leading to the clinical outcomes observed in AD. Besides deficits in glucose uti...

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Bibliographic Details
Main Authors: Fernanda G. De Felice, Mychael V Lourenco
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00094/full