Altered cord blood mitochondrial DNA content and pregnancy lead exposure in the PROGRESS cohort

Introduction: Lead (Pb) crosses the placenta and can cause oxidative stress, reduced fetal growth and neurological problems. The principal source of oxidative stress in human cells is mitochondria. Therefore, disruption of normal mitochondrial function during pregnancy may represent a primary mechan...

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Bibliographic Details
Main Authors: Marco Sanchez-Guerra, Cheng Peng, Letizia Trevisi, Andres Cardenas, Ander Wilson, Citlalli Osorio-Yáñez, Megan M. Niedzwiecki, Jia Zhong, Katherine Svensson, Maria Teresa Acevedo, Maritsa Solano-Gonzalez, Chitra J. Amarasiriwardena, Guadalupe Estrada-Gutierrez, Kasey J.M. Brennan, Lourdes Schnaas, Allan C. Just, Hannah E. Laue, Rosalind J. Wright, Martha Maria Téllez-Rojo, Robert O. Wright, Andrea A. Baccarelli
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412018313801