Mycobacteria-Specific T Cells May Be Expanded From Healthy Donors and Are Near Absent in Primary Immunodeficiency Disorders
Mycobacterial Infections can be severe in patients with T-cell deficiency or phagocyte disorders, and treatment is frequently complicated by antimicrobial resistance. Restoration of T-cell immunity via stem cell transplantation facilitates control of mycobacterial infections, but presence of active...
Main Authors: | Shabnum Patel, Haili Lang, Gelina Sani, Alexandra F. Freeman, Jennifer Leiding, Patrick J. Hanley, Conrad Russell Cruz, Melanie Grant, Yunfei Wang, Benjamin Oshrine, Cindy Palmer, Steven M. Holland, Catherine M. Bollard, Michael D. Keller |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-03-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.00621/full |
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