Chondrocytes from Osteoarthritis Patients Adopt Distinct Phenotypes in Response to Central T<sub>H</sub>1/T<sub>H</sub>2/T<sub>H</sub>17 Cytokines

Chondrocytes from Osteoarthritis Patients Adopt Distinct Phenotypes in Response to Central T<sub>H</sub>1/T<sub>H</sub>2/T<sub>H</sub>17 Cytokines

Chronic low-grade inflammation plays a central role in the pathogenesis of osteoarthritis (OA), and several pro- and anti-inflammatory cytokines have been implicated to mediate and regulate this process. Out of these cytokines, particularly IFNγ, IL-1β, IL-4 and IL-17 are associated with different p...

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Bibliographic Details
Main Authors: Antti Pemmari, Tiina Leppänen, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
chondrocyte
IL-1β
IFNγ, IL-17
IL-4
RNA-Seq
Online Access:https://www.mdpi.com/1422-0067/22/17/9463

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https://www.mdpi.com/1422-0067/22/17/9463

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