β2-Glycoprotein I-Reactive T Cells in Autoimmune Disease

β2-Glycoprotein I-Reactive T Cells in Autoimmune Disease

Anti-phospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases characterized by autoantibody production and autoantibody-related pathology. Anti-phospholipid antibodies (aPL) are found in all patients with APS and in 20–30% of individuals with SLE. aPL recognize a nu...

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Bibliographic Details
Main Authors: Joyce Rauch, David Salem, Rebecca Subang, Masataka Kuwana, Jerrold S. Levine
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
β2-glycoprotein I
T cells
systemic lupus erythematosus
anti-phospholipid syndrome
autoantibodies
MHC class II haplotypes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02836/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02836/full

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