CoQ10 augments candesartan protective effect against tourniquet-induced hind limb ischemia-reperfusion: Involvement of non-classical RAS and ROS pathways

CoQ10 augments candesartan protective effect against tourniquet-induced hind limb ischemia-reperfusion: Involvement of non-classical RAS and ROS pathways

Tourniquet is a well-established model of hind limb ischemia–reperfusion (HLI/R) in rats. Nevertheless, measures should be taken to alleviate the expected injury from ischemia/ reperfusion (I/R). In the present study, 30 adult male Sprague-Dawley rats were randomly divided into 5 groups (n = 6): con...

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Bibliographic Details
Main Authors: Azza S. Awad, Mahmoud Nour El-Din, Rehab Kamel
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Saudi Pharmaceutical Journal
Subjects:
Candesartan
CoQ10
ACE-2
Renin angiotensin system
Tourniquet
Mas receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016421001018

Internet

http://www.sciencedirect.com/science/article/pii/S1319016421001018

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