Tonic levels of angiotensin II reduce tonic levels of vascular nitric oxide even in salt-replete man

Introduction Losartan improves stimulated endothelial function in patients with cardiovascular disease, but there are no data to establish whether losartan has this effect in normal man. Furthermore, whether losartan improves basal nitric oxide (NO) activity is controversial. We therefore examined w...

Full description

Bibliographic Details
Main Authors: Justein SN Sim, Colin Farquharson, Allan D Struthers
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2004-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2004.015