Resuscitation of Dormant “Non-culturable” Mycobacterium tuberculosis Is Characterized by Immediate Transcriptional Burst

Resuscitation of Dormant “Non-culturable” Mycobacterium tuberculosis Is Characterized by Immediate Transcriptional Burst

Under unfavorable conditions such as host immune responses and environmental stresses, human pathogen Mycobacterium tuberculosis may acquire the dormancy phenotype characterized by “non-culturability” and a substantial decrease of metabolic activity and global transcription rates. Here, we found tha...

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Bibliographic Details
Main Authors: Elena G. Salina, Artem S. Grigorov, Oksana S. Bychenko, Yulia V. Skvortsova, Ilgar Z. Mamedov, Tatyana L. Azhikina, Arseny S. Kaprelyants
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
resuscitation
M. tuberculosis
non-culturability
dormancy
transcriptional burst
small non-coding RNAs
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00272/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00272/full

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