Vorinostat: a histone deacetylases (HDAC) inhibitor ameliorates traumatic brain injury by inducing iNOS/Nrf2/ARE pathway
The present investigation evaluates the protective effect of vorinostat on neuronal cells in the traumatic brain injury (TBI) and also postulates the possible mechanism of its action. Marmarou’s weight-drop model was used to induce the TBI. Further, animals were treated with vorinostat 100 mg/kg int...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2018-09-01
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| Series: | Folia Neuropathologica |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Vorinostat-a-histone-deacetylases-HDAC-inhibitor-ameliorates-traumatic-brain-injury-by-inducing-iNOS-Nrf2-ARE-pathway,20,33882,1,1.html |