Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancement

Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancement

<p>Abstract</p> <p>Background</p> <p>Dengue viruses (DENV) are the most important arboviruses of humans and cause significant disease. Infection with DENV elicits antibody responses to the envelope glycoprotein, predominantly against immunodominant, cross-reactive, weak...

Full description

Bibliographic Details
Main Authors: Hughes Holly R, Crill Wayne D, Chang Gwong-Jen J
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Virology Journal
Subjects:
Dengue virus
Vaccine
Antibody-dependent enhancement
Dengue hemorrhagic fever
Cross-reactive antibody
Immune refocusing
Online Access:http://www.virologyj.com/content/9/1/115

Internet

http://www.virologyj.com/content/9/1/115

Similar Items