Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates.

Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates.

In order to maintain visual sensitivity at all light levels, the vertebrate eye possesses a mechanism to regenerate the visual pigment chromophore 11-cis retinal in the dark enzymatically, unlike in all other taxa, which rely on photoisomerization. This mechanism is termed the visual cycle and is lo...

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Bibliographic Details
Main Authors: Eugenia Poliakov, Alexander N Gubin, Olivia Stearn, Yan Li, Maria Mercedes Campos, Susan Gentleman, Igor B Rogozin, T Michael Redmond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3507948?pdf=render

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http://europepmc.org/articles/PMC3507948?pdf=render

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