Protective Effect and Mechanism of Bone Morphogenetic Protein-4 on Apoptosis of Human Lens Epithelium Cells under Oxidative Stress

Bone morphogenetic proteins (BMPs), a member of the transforming growth factor β (TGF-β) superfamily, are abundant in human ocular tissues and play an important role in lens development. Targeted deletion of BMP-4 in mice results in failure of lens placode formation. Following lens maturation, the f...

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Bibliographic Details
Main Authors: Bei Du, Jia-Lin Zheng, Liang-Yu Huang, Hong Zhang, Qiong Wang, Ya-Ru Hong, Xiao-min Zhang, Xiao-Rong Li, Li-Jie Dong
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/8109134