Hypoxia-induced invadopodia formation: a role for β-PIX

During tumour progression, oxygen tension in the microenvironment surrounding tumour cells is reduced, resulting in hypoxia. It is well established that cancer cells resist the negative effects of hypoxia by inducing angiogenesis predominantly via the activity of transcription factor hypoxia-inducib...

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Bibliographic Details
Main Authors: Nur Fariesha Md Hashim, Nicole S. Nicholas, Anna E. Dart, Serafim Kiriakidis, Ewa Paleolog, Claire M. Wells
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120159