Modulation of SUR1 K<sub>ATP</sub> Channel Subunit Activity in the Peripheral Nervous System Reduces Mechanical Hyperalgesia after Nerve Injury in Mice

The ATP-sensitive K<sup>+</sup> channel (K<sub>ATP</sub>) is involved in hypersensitivity during chronic pain and is presumed to be a downstream target of mu opioid receptors. Multiple subtypes of K<sub>ATP</sub> channels exist in the peripheral and central nervou...

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Bibliographic Details
Main Authors: Wing Luu, James Bjork, Erin Salo, Nicole Entenmann, Taylor Jurgenson, Cole Fisher, Amanda H. Klein
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/9/2251