Prediction of Malignant Transformation of WHO II Astrocytoma Using Mathematical Models Incorporating Apparent Diffusion Coefficient and Contrast Enhancement

Prediction of Malignant Transformation of WHO II Astrocytoma Using Mathematical Models Incorporating Apparent Diffusion Coefficient and Contrast Enhancement

Using only increasing contrast enhancement as a marker of malignant transformation (MT) in gliomas has low specificity and may affect interpretation of clinical outcomes. Therefore we developed a mathematical model to predict MT of low-grade gliomas (LGGs) by considering areas of reduced apparent di...

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Bibliographic Details
Main Authors: Alex Mun-Ching Wong, Tiing Yee Siow, Kuo-Chen Wei, Pin-Yuan Chen, Cheng Hong Toh, Mauricio Castillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
malignant transformation
contrast enhancement
apparent diffusion coefficient
model prediction and validation
low-grade gliomas
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.744827/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.744827/full

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