Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC

Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC

Abstract Background Chemoresistance is a primary clinical challenge for the management of small cell lung cancer. Additionally, transcriptional regulation by super enhancer (SE) has an important role in tumor evolution. The functions of SEs, a key class of noncoding DNA cis-regulatory elements, have...

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Bibliographic Details
Main Authors: Jiarong Bao, Man Li, Shumei Liang, Yunchu Yang, Jingfang Wu, Qingqing Zou, Shun Fang, Size Chen, Linlang Guo
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Medical Genomics
Subjects:
Small cell lung cancer
Chemoresistance
Super enhancer
Online Access:http://link.springer.com/article/10.1186/s12920-019-0520-9

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http://link.springer.com/article/10.1186/s12920-019-0520-9

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