The Mechanism of β2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish

Summary: Contemporary antigen presentation knowledge is based on the existence of a single β2m locus, and a classical MHC class I forms a complex with a peptide (i.e., pMHC-I) to trigger CTL immunity. However, two β2m loci have been found in diploid bony fish; the function of the two β2m molecules i...

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Bibliographic Details
Main Authors: Zibin Li, Nianzhi Zhang, Lizhen Ma, Lijie Zhang, Geng Meng, Chun Xia
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220303047