Genome-wide RNAi Screen Identifies SEC61A and VCP as Conserved Regulators of Sindbis Virus Entry

Genome-wide RNAi Screen Identifies SEC61A and VCP as Conserved Regulators of Sindbis Virus Entry

Alphaviruses are a large class of insect-borne human pathogens and little is known about the host-factor requirements for infection. To identify such factors, we performed a genome-wide RNAi screen using model Drosophila cells and validated 94 genes that impacted infection of Sindbis virus (SINV),...

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Bibliographic Details
Main Authors: Debasis Panda, Patrick P. Rose, Sheri L. Hanna, Beth Gold, Kaycie C. Hopkins, Randolph B. Lyde, Michael S. Marks, Sara Cherry
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713006955

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http://www.sciencedirect.com/science/article/pii/S2211124713006955

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