IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C.

Although, the treatment of chronic hepatitis C (CHC) greatly improved with the use of direct antiviral agents, pegylated-interferon (PEG-IFN) plus ribavirin remains an option for many patients, worldwide. The intra-hepatic level of expression of interferon stimulated genes (ISGs) and the rs12979860...

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Main Authors: Emilie Estrabaud, Kevin Appourchaux, Ivan Bièche, Fabrice Carrat, Martine Lapalus, Olivier Lada, Michelle Martinot-Peignoux, Nathalie Boyer, Patrick Marcellin, Michel Vidaud, Tarik Asselah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4386819?pdf=render