What We Know and Would Like to Know about CDKL5 and Its Involvement in Epileptic Encephalopathy

In the last few years, the X-linked serine/threonine kinase cyclin-dependent kinase-like 5 (CDKL5) has been associated with early-onset epileptic encephalopathies characterized by the manifestation of intractable epilepsy within the first weeks of life, severe developmental delay, profound hypotonia...

Full description

Bibliographic Details
Main Authors: Charlotte Kilstrup-Nielsen, Laura Rusconi, Paolo La Montanara, Dalila Ciceri, Anna Bergo, Francesco Bedogni, Nicoletta Landsberger
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2012/728267