SIRT1 expression is associated with the chemotherapy response and prognosis of patients with advanced NSCLC.

AIM: The role of Sirtuin 1 (SIRT 1) in carcinogenesis is controversial. This study was to explore the association between the SIRT1 expression and the clinical characteristics, the responsiveness to chemotherapy and prognosis in Non-small cell lung cancer (NSCLC). METHODS: We enrolled 295 patients w...

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Bibliographic Details
Main Authors: Tao Zhang, Ningning Rong, Juan Chen, Chengwei Zou, Haiyan Jing, Xiaolong Zhu, Wenlong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818418?pdf=render