Prediction and Evolution of the Molecular Fitness of SARS-CoV-2 Variants: Introducing SpikePro

The understanding of the molecular mechanisms driving the fitness of the SARS-CoV-2 virus and its mutational evolution is still a critical issue. We built a simplified computational model, called SpikePro, to predict the SARS-CoV-2 fitness from the amino acid sequence and structure of the spike prot...

Full description

Bibliographic Details
Main Authors: Fabrizio Pucci, Marianne Rooman
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/5/935