Induction of apoptosis and inhibition of cell growth by <it>tbx5 </it>knockdown contribute to dysmorphogenesis in Zebrafish embryos

Induction of apoptosis and inhibition of cell growth by <it>tbx5 </it>knockdown contribute to dysmorphogenesis in Zebrafish embryos

<p>Abstract</p> <p>Background</p> <p>The tbx5 mutation in human causes Holt-Oram syndrome, an autosomal dominant condition characterized by a familial history of congenital heart defects and preaxial radial upper-limb defects. We report aberrant apoptosis and dormant ce...

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Bibliographic Details
Main Authors: Tang Renbing, Yeh Shuyu, Choo Sielin, Tsai Tzuchun, Lu Jenher, Yang Anhang, Lee Hsinyu, Lu Jennkan
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Biomedical Science
Subjects:
zebrafish
mitochondria
apoptosis
<it>tbx5</it>
Holt-Oram syndrome
cell cycle
Online Access:http://www.jbiomedsci.com/content/18/1/73

Internet

http://www.jbiomedsci.com/content/18/1/73

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