An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism.
Methionine (Met) is an essential amino acid that is needed for the synthesis of S-adenosylmethionine (AdoMet), the major biological methylating agent. Methionine used for AdoMet synthesis can be replenished via remethylation of homocysteine. Alternatively, homocysteine can be converted to cysteine v...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2346559?pdf=render |