An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism.

Methionine (Met) is an essential amino acid that is needed for the synthesis of S-adenosylmethionine (AdoMet), the major biological methylating agent. Methionine used for AdoMet synthesis can be replenished via remethylation of homocysteine. Alternatively, homocysteine can be converted to cysteine v...

Full description

Bibliographic Details
Main Authors: Tatyana K Korendyaseva, Denis N Kuvatov, Vladimir A Volkov, Michael V Martinov, Victor M Vitvitsky, Ruma Banerjee, Fazoil I Ataullakhanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2346559?pdf=render