Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFβ1-signaling and increased Galectin-3 expression: A histological study on biopsies

Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFβ1-signaling and increased Galectin-3 expression: A histological study on biopsies

<p>Abstract</p> <p>Background</p> <p>Bisphosphonate associated osteonecrosis of the jaw (BRONJ) implies an impairment in oral hard- and soft tissue repair. An understanding of the signal transduction alterations involved can inform therapeutic strategies. Transforming g...

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Bibliographic Details
Main Authors: Schlegel Karl A, Stockmann Phillip, Nkenke Emeka, Guentsch Arndt, Hyckel Peter, Wehrhan Falk, Neukam Friedrich W, Amann Kerstin
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Journal of Translational Medicine
Subjects:
BRONJ
oral soft tissue
transforming growth factor beta 1
galectin-3
oral surgery
Online Access:http://www.translational-medicine.com/content/9/1/102

Internet

http://www.translational-medicine.com/content/9/1/102

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