The Green Tea Component (-)-Epigallocatechin-3-Gallate Sensitizes Primary Endothelial Cells to Arsenite-Induced Apoptosis by Decreasing c-Jun N-Terminal Kinase-Mediated Catalase Activity.

The green tea component (-)-epigallocatechin-3-gallate (EGCG) has been shown to sensitize many different types of cancer cells to anticancer drug-induced apoptosis, although it protects against non-cancerous primary cells against toxicity from certain conditions such as exposure to arsenic (As) or u...

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Main Authors: Jee-Youn Kim, Ji-Young Choi, Hyeon-Ju Lee, Catherine Jeonghae Byun, Jung-Hyun Park, Jae Hoon Park, Ho-Seong Cho, Sung-Jin Cho, Sangmee Ahn Jo, Inho Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574201?pdf=render