IVIVC from Long Acting Olanzapine Microspheres

In this study, four PLGA microsphere formulations of Olanzapine were characterized on the basis of their in vitro behavior at 37°C, using a dialysis based method, with the goal of obtaining an IVIVC. In vivo profiles were determined by deconvolution (Nelson-Wagner method) and using fractional AUC....

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Bibliographic Details
Main Authors: Susan D'Souza, Jabar A. Faraj, Stefano Giovagnoli, Patrick P. DeLuca
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2014/407065