IVIVC from Long Acting Olanzapine Microspheres
In this study, four PLGA microsphere formulations of Olanzapine were characterized on the basis of their in vitro behavior at 37°C, using a dialysis based method, with the goal of obtaining an IVIVC. In vivo profiles were determined by deconvolution (Nelson-Wagner method) and using fractional AUC....
Main Authors: | Susan D'Souza, Jabar A. Faraj, Stefano Giovagnoli, Patrick P. DeLuca |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | International Journal of Biomaterials |
Online Access: | http://dx.doi.org/10.1155/2014/407065 |
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