Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a single-centre laboratory evaluation study

Summary: Background: Lateral flow devices (LFDs) for rapid antigen testing are set to become a cornerstone of SARS-CoV-2 mass community testing, although their reduced sensitivity compared with PCR has raised questions of how well they identify infectious cases. Understanding their capabilities and...

Full description

Bibliographic Details
Main Authors: Suzanne Pickering, PhD, Rahul Batra, MD, Blair Merrick, MBChB, Luke B Snell, MBBS, Gaia Nebbia, FRCPath, Sam Douthwaite, MRCP, Fiona Reid, MSc, Amita Patel, BSc, Mark Tan Kia Ik, BSc, Bindi Patel, BSc, Themoula Charalampous, PhD, Adela Alcolea-Medina, MPhil, Maria Jose Lista, PhD, Penelope R Cliff, PhD, Emma Cunningham, MSc, Jane Mullen, BSc, Katie J Doores, PhD, Jonathan D Edgeworth, ProfFRCPath, Michael H Malim, ProfDPhil, Stuart J D Neil, ProfPhD, Rui Pedro Galão, PhD
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524721001439