Efficient generation of multipotent mesenchymal stem cells from umbilical cord blood in stroma-free liquid culture.

BACKGROUND: Haematopoiesis is sustained by haematopoietic (HSC) and mesenchymal stem cells (MSC). HSC are the precursors for blood cells, whereas marrow, stroma, bone, cartilage, muscle and connective tissues derive from MSC. The generation of MSC from umbilical cord blood (UCB) is possible, but wit...

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Bibliographic Details
Main Authors: Rowayda Peters, Monika J Wolf, Maries van den Broek, Mario Nuvolone, Stefanie Dannenmann, Bruno Stieger, Reto Rapold, Daniel Konrad, Arnold Rubin, Joseph R Bertino, Adriano Aguzzi, Mathias Heikenwalder, Alexander K Knuth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3012708?pdf=render