The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice.

The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice.

Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is mediated by phagocytic cells and by Borrelia-specific complement-ac...

Full description

Bibliographic Details
Main Authors: Michal Krupka, Josef Masek, Lucia Barkocziova, Pavlina Turanek Knotigova, Pavel Kulich, Jana Plockova, Robert Lukac, Eliska Bartheldyova, Stepan Koudelka, Radka Chaloupkova, Marek Sebela, Daniel Zyka, Ladislav Droz, Roman Effenberg, Miroslav Ledvina, Andrew D Miller, Jaroslav Turanek, Milan Raska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4744052?pdf=render

Internet

http://europepmc.org/articles/PMC4744052?pdf=render

Similar Items