ROS Dependent Wnt/β-Catenin Pathway and Its Regulation on Defined Micro-Pillars—A Combined In Vitro and In Silico Study

ROS Dependent Wnt/β-Catenin Pathway and Its Regulation on Defined Micro-Pillars—A Combined In Vitro and In Silico Study

The physico-chemical surface design of implants influences the surrounding cells. Osteoblasts on sharp-edged micro-topographies revealed an impaired cell phenotype, function and Ca<sup>2+</sup> mobilization. The influence of edges and ridges on the Wnt/β-catenin pathway in combination wi...

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Bibliographic Details
Main Authors: Susanne Staehlke, Fiete Haack, Anna-Christin Waldner, Dirk Koczan, Caroline Moerke, Petra Mueller, Adelinde M. Uhrmacher, J. Barbara Nebe
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
human osteoblastic cells
micro-pillars
canonical Wnt pathway
β-catenin
microarray
gene profiling
Online Access:https://www.mdpi.com/2073-4409/9/8/1784

Internet

https://www.mdpi.com/2073-4409/9/8/1784

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