Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity

Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity

In the present study, we aimed to investigate the impact of permanent cystathionine-β-Synthase (CBS) gene knockdown in human telomerase reverse transcriptase (hTERT) immortalized human adipose-derived mesenchymal stem cells (ASC52telo) and in their capacity to differentiate into adipocytes. CBS gene...

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Bibliographic Details
Main Authors: Ferran Comas, Jèssica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Aina Lluch, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Redox Biology
Subjects:
Human adipose-derived mesenchymal stem cells
Cystathionine β-synthase
Cellular senescence
Inflammation
Oxidative stress and adipogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308739

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http://www.sciencedirect.com/science/article/pii/S2213231720308739

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