On the origin of DNA genomes: evolution of the division of labor between template and catalyst in model replicator systems.

The division of labor between template and catalyst is a fundamental property of all living systems: DNA stores genetic information whereas proteins function as catalysts. The RNA world hypothesis, however, posits that, at the earlier stages of evolution, RNA acted as both template and catalyst. Why...

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Bibliographic Details
Main Authors: Nobuto Takeuchi, Paulien Hogeweg, Eugene V Koonin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3063752?pdf=render