Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and precursor miRNA.

Bibliographic Details
Main Authors: Xiaoyi Fu, Guoliang Ke, Fangqi Peng, Xue Hu, Jiaqi Li, Yuyan Shi, Gezhi Kong, Xiao-Bing Zhang, Weihong Tan
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15297-7