Reliability and reproducibility of a rodent model of choroidal neovascularization based on the subretinal injection of polyethylene glycol

Purpose: To evaluate the reliability and reproducibility of a rodent choroidal neovascularization (CNV) model by subretinal injection of polyethylene glycol (PEG). Methods: C57BL/6 mice were injected subretinally with 2 μl PBS (Gibco, Invitrogen, Paisley, UK; n=14) or PEG (1 mg; n=18). Animals we...

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Bibliographic Details
Main Authors: Ivan Fernandez-Bueno, Maria-Luz Alonso-Alonso, Maria-Teresa Garcia-Gutierrez, Yolanda Diebold
Format: Article
Language:English
Published: Molecular Vision 2019-03-01
Series:Molecular Vision
Subjects:
Online Access:http://www.molvis.org/molvis/v25/194/