A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Significant departures from expected Mendelian inheritance ratios (transmission ratio distortion, TRD) are frequently observed in both experimental crosses and natural populations. TRD on mouse Chromosome (Chr) 2 has been reported in multiple experimental crosses, including the Collaborative Cross (...

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Bibliographic Details
Main Authors: John P Didion, Andrew P Morgan, Amelia M-F Clayshulte, Rachel C Mcmullan, Liran Yadgary, Petko M Petkov, Timothy A Bell, Daniel M Gatti, James J Crowley, Kunjie Hua, David L Aylor, Ling Bai, Mark Calaway, Elissa J Chesler, John E French, Thomas R Geiger, Terry J Gooch, Theodore Garland, Alison H Harrill, Kent Hunter, Leonard McMillan, Matt Holt, Darla R Miller, Deborah A O'Brien, Kenneth Paigen, Wenqi Pan, Lucy B Rowe, Ginger D Shaw, Petr Simecek, Patrick F Sullivan, Karen L Svenson, George M Weinstock, David W Threadgill, Daniel Pomp, Gary A Churchill, Fernando Pardo-Manuel de Villena
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4334553?pdf=render

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http://europepmc.org/articles/PMC4334553?pdf=render

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