Viral UL8 Is Involved in the Antiviral Activity of Oleanolic Acid Against HSV-1 Infection

Viral UL8 Is Involved in the Antiviral Activity of Oleanolic Acid Against HSV-1 Infection

Herpes simplex virus type 1 (HSV-1) is highly prevalent in humans and can cause severe diseases, especially in immunocompromised adults and newborns, such as keratitis and herpes simplex encephalitis. At present, the clinical therapeutic drug against HSV-1 infection is acyclovir (ACV), and its exten...

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Bibliographic Details
Main Authors: Tianhao Shan, Ju Ye, Jiaoyan Jia, Zhaoyang Wang, Yuzhou Jiang, Yiliang Wang, Yifei Wang, Kai Zheng, Zhe Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Microbiology
Subjects:
herpes simplex virus type 1
Oleanolic acid
UL8
helicase-primase complex
zosteriform model
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.689607/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.689607/full

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