Pharmacokinetics and Bioequivalence of Rasagiline Tablets in Chinese Healthy Subjects Under Fasting and Fed Conditions: An Open, Randomized, Single-Dose, Double-Cycle, Two-Sequence, Crossover Trial

Pharmacokinetics and Bioequivalence of Rasagiline Tablets in Chinese Healthy Subjects Under Fasting and Fed Conditions: An Open, Randomized, Single-Dose, Double-Cycle, Two-Sequence, Crossover Trial

Objective: This study evaluated the pharmacokinetics, safety, and bioequivalence (BE) of two formulations of rasagiline tablets in healthy Chinese subjects under fasting and fed conditions.Methods: An open, randomized, single-dose, double-cycle, two-sequence, self-crossover pharmacokinetic study in...

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Bibliographic Details
Main Authors: Yinjuan Li, Lu Qi, Haihong Bai, Ying Liu, Rongxia Fan, Yongrui Tu, Yongqiang Sun, Juxiang Wang, Qi Qi, Xiaohui Feng, Da Zhou, Xinghe Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
bioequivalence
rasagiline
pharmacokinetic
food effect
highly variable drug
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.571747/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.571747/full

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