Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals

Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals

Over the last two decades, awareness of the negative repercussions of flaws in the planning, conduct and reporting of preclinical research involving experimental animals has been growing. Several initiatives have set out to increase transparency and internal validity of preclinical studies, mostly p...

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Main Authors: Merel Ritskes-Hoitinga, Ulrich Dirnagl, Malcolm Macleod, Thomas Steckler, Jan Vollert, Esther Schenker, Anton Bespalov, Hanno Wuerbel, Heidrun Potschka, Kimberley E Wever, Bruce Altevogt, Andrew S C Rice, Judi Clark, Emily Sena, Bruno Boulanger, Gernot Riedel, Bettina Platt, Annesha Sil, Martien J Kas, Bernhard Voelkl, Mathias Jucker, Bettina M Wegenast-braun, René Bernard, Esmeralda Heiden, Ann-marie Waldron, Maarten Loos, Pim Drinkenburg, Juan Diego Pita almenar, David Gallacher, Anja Gilis, Greet Teuns, Karsten Wicke, Sabine Grote, Bernd Sommer, Janet Nicholson, Sanna Janhunen, Sami Virtanen, Kristin Cheng, Sylvie Ramboz, Emer Leahy, Isabel A Lefevre, Fiona Ducrey, Javier Guillen, Patri Vergara, Kimberley Wever, Martin Michel, Tom van de Casteele, Martin C Michel, Tom Van De Casteele, Henk Van Der Linde, Isabel Seiffert
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:BMJ Open Science
Online Access:https://openscience.bmj.com/content/4/1/e100046.full

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https://openscience.bmj.com/content/4/1/e100046.full

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