The Increase of ROS Caused by the Interference of DEHP with JNK/p38/p53 Pathway as the Reason for Hepatotoxicity

As the most commonly used plasticizer, Di-(2-ethylhexyl)-phthalate (DEHP) exists everywhere in the environment due to the widespread use of polyvinyl chloride (PVC) in human life, and it is also a recognized environmental pollutant. Studies have proved the hepatotoxicity of DEHP, however the mechani...

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Bibliographic Details
Main Authors: Yuanyuan Huang, Chuancheng Wu, Youbin Ye, Jingwen Zeng, Jianlin Zhu, Yuchen Li, Wenxiang Wang, Wenchang Zhang, Yiqin Chen, Hongyuan Xie, Hongmei Zhang, Jin Liu
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Environmental Research and Public Health
Subjects:
ROS
Online Access:https://www.mdpi.com/1660-4601/16/3/356