M cell-dependent antigen uptake on follicle-associated epithelium for mucosal immune surveillance

Abstract The follicle-associated epithelium (FAE) covering mucosa-associated lymphoid tissue is distinct from the villous epithelium in cellular composition and functions. Interleukin-22 binding protein (IL-22BP), provided by dendritic cells at the sub-epithelial dome region, inhibits the IL-22-medi...

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Bibliographic Details
Main Authors: Yutaka Nakamura, Shunsuke Kimura, Koji Hase
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Inflammation and Regeneration
Subjects:
FAE
Online Access:http://link.springer.com/article/10.1186/s41232-018-0072-y